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il-6 mediator  (Thermo Fisher)


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    Thermo Fisher il-6 mediator
    Il 6 Mediator, supplied by Thermo Fisher, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/il-6 mediator/product/Thermo Fisher
    Average 90 stars, based on 1 article reviews
    il-6 mediator - by Bioz Stars, 2026-02
    90/100 stars

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    Inflammatory cytokine levels in the PFC, STR and HP 1 h after last JNJ/SBE + AMPH/SAL injections Expression of pro- and anti-inflammatory cytokine levels were measured by CBA FACS analysis in WT mice. (A) IL-1β. (B) IL-4. (C) IL-6. (D) IL-10. (E) <t>IFN-γ.</t> (F) TNF-α. Values are presented as means ± SEM of n = 7 mice per group. We compared the effect of treatments on cytokine levels per brain area. One-way ANOVA followed by Tukey’s multiple comparison post hoc test (with or without square root transformation) or Kruskal-Wallis test with multiple comparisons was done: ∗p < 0.05, ∗∗p < 0.01 compared to the SBE + SAL treated group, # p < 0.05, ## p < 0.01, ### p < 0.001 compared to the SBE + AMPH treated group in a same genotype. AMPH, d-amphetamine, HP, hippocampus, IFN, interferon; IL, interleukin; JNJ, JNJ-47965567, PFC, prefrontal cortex, SAL, saline, SBE, beta cyclodextrin sulfobutyl ether, STR, striatum, TNF, tumor necrosis factor, WT, wild-type mice.
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    Inflammatory cytokine levels in the PFC, STR and HP 1 h after last JNJ/SBE + AMPH/SAL injections Expression of pro- and anti-inflammatory cytokine levels were measured by CBA FACS analysis in WT mice. (A) IL-1β. (B) IL-4. (C) IL-6. (D) IL-10. (E) IFN-γ. (F) TNF-α. Values are presented as means ± SEM of n = 7 mice per group. We compared the effect of treatments on cytokine levels per brain area. One-way ANOVA followed by Tukey’s multiple comparison post hoc test (with or without square root transformation) or Kruskal-Wallis test with multiple comparisons was done: ∗p < 0.05, ∗∗p < 0.01 compared to the SBE + SAL treated group, # p < 0.05, ## p < 0.01, ### p < 0.001 compared to the SBE + AMPH treated group in a same genotype. AMPH, d-amphetamine, HP, hippocampus, IFN, interferon; IL, interleukin; JNJ, JNJ-47965567, PFC, prefrontal cortex, SAL, saline, SBE, beta cyclodextrin sulfobutyl ether, STR, striatum, TNF, tumor necrosis factor, WT, wild-type mice.

    Journal: iScience

    Article Title: P2X7 receptor inhibition alleviates mania-like behavior independently of interleukin-1β

    doi: 10.1016/j.isci.2024.109284

    Figure Lengend Snippet: Inflammatory cytokine levels in the PFC, STR and HP 1 h after last JNJ/SBE + AMPH/SAL injections Expression of pro- and anti-inflammatory cytokine levels were measured by CBA FACS analysis in WT mice. (A) IL-1β. (B) IL-4. (C) IL-6. (D) IL-10. (E) IFN-γ. (F) TNF-α. Values are presented as means ± SEM of n = 7 mice per group. We compared the effect of treatments on cytokine levels per brain area. One-way ANOVA followed by Tukey’s multiple comparison post hoc test (with or without square root transformation) or Kruskal-Wallis test with multiple comparisons was done: ∗p < 0.05, ∗∗p < 0.01 compared to the SBE + SAL treated group, # p < 0.05, ## p < 0.01, ### p < 0.001 compared to the SBE + AMPH treated group in a same genotype. AMPH, d-amphetamine, HP, hippocampus, IFN, interferon; IL, interleukin; JNJ, JNJ-47965567, PFC, prefrontal cortex, SAL, saline, SBE, beta cyclodextrin sulfobutyl ether, STR, striatum, TNF, tumor necrosis factor, WT, wild-type mice.

    Article Snippet: Concentration of anti- and proinflammatory mediators IFN-γ (RRID: AB_2869141 ), IL-1β (RRID: AB_2869322 ), IL-4 (RRID: AB_2869143 ), IL-6 (RRID: AB_2869146 ), IL-10 (RRID: AB_2869145 ), TNF-α (RRID: AB_2869144 ) were measured from plasma and brain samples using a BD FACSVerse flow cytometer, Cytometric Bead Array Kit (BD Biosciences, San Jose, CA, US, Cat# 558267).

    Techniques: Expressing, Comparison, Transformation Assay, Saline

    Inflammatory cytokine levels in the PFC, STR and HP 1 h after last SBE + AMPH/SAL injections in IL-1αβKO mice Expression of pro- and anti-inflammatory cytokine levels were measured by CBA analysis in IL-1αβKO mice. (A) IL-1β. (B) IL-4. (C) IL-6. (D) IL-10. (E) IFN-γ. (F) TNF-α. Values are presented as means ± SEM of n = 7 mice per group. We compared the effect of AMPH treatment on cytokine levels in different brain areas. Mann-Whitney U Test or Student’s t test were done (with or without square root transformation) were done: ∗p < 0.05, ∗∗p < 0.01 compared SBE + SAL treated group. AMPH, d-amphetamine, HP, hippocampus, IFN, interferon; IL, interleukin; IL-1αβKO, interleukin-1α/β knockout mice, PFC, prefrontal cortex, SAL, saline, SBE, beta cyclodextrin sulfobutyl ether, STR, striatum, TNF, tumor necrosis factor.

    Journal: iScience

    Article Title: P2X7 receptor inhibition alleviates mania-like behavior independently of interleukin-1β

    doi: 10.1016/j.isci.2024.109284

    Figure Lengend Snippet: Inflammatory cytokine levels in the PFC, STR and HP 1 h after last SBE + AMPH/SAL injections in IL-1αβKO mice Expression of pro- and anti-inflammatory cytokine levels were measured by CBA analysis in IL-1αβKO mice. (A) IL-1β. (B) IL-4. (C) IL-6. (D) IL-10. (E) IFN-γ. (F) TNF-α. Values are presented as means ± SEM of n = 7 mice per group. We compared the effect of AMPH treatment on cytokine levels in different brain areas. Mann-Whitney U Test or Student’s t test were done (with or without square root transformation) were done: ∗p < 0.05, ∗∗p < 0.01 compared SBE + SAL treated group. AMPH, d-amphetamine, HP, hippocampus, IFN, interferon; IL, interleukin; IL-1αβKO, interleukin-1α/β knockout mice, PFC, prefrontal cortex, SAL, saline, SBE, beta cyclodextrin sulfobutyl ether, STR, striatum, TNF, tumor necrosis factor.

    Article Snippet: Concentration of anti- and proinflammatory mediators IFN-γ (RRID: AB_2869141 ), IL-1β (RRID: AB_2869322 ), IL-4 (RRID: AB_2869143 ), IL-6 (RRID: AB_2869146 ), IL-10 (RRID: AB_2869145 ), TNF-α (RRID: AB_2869144 ) were measured from plasma and brain samples using a BD FACSVerse flow cytometer, Cytometric Bead Array Kit (BD Biosciences, San Jose, CA, US, Cat# 558267).

    Techniques: Expressing, MANN-WHITNEY, Transformation Assay, Knock-Out, Saline

    Journal: iScience

    Article Title: P2X7 receptor inhibition alleviates mania-like behavior independently of interleukin-1β

    doi: 10.1016/j.isci.2024.109284

    Figure Lengend Snippet:

    Article Snippet: Concentration of anti- and proinflammatory mediators IFN-γ (RRID: AB_2869141 ), IL-1β (RRID: AB_2869322 ), IL-4 (RRID: AB_2869143 ), IL-6 (RRID: AB_2869146 ), IL-10 (RRID: AB_2869145 ), TNF-α (RRID: AB_2869144 ) were measured from plasma and brain samples using a BD FACSVerse flow cytometer, Cytometric Bead Array Kit (BD Biosciences, San Jose, CA, US, Cat# 558267).

    Techniques: Recombinant, Enzyme-linked Immunosorbent Assay, Bicinchoninic Acid Protein Assay, Multiple Displacement Amplification, Double Knockout, Knock-Out, Software, FCAP Assay